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World of the Large Steam Sterilizers

Our large autoclaves
For large sterilization volume.

You need to reprocess large quantities of sterilized items efficiently and reliably? Our large autoclaves with an capacity of up to 200 litres meet every requirement in practices, clinics and hospitals.

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Vacuclave 550

Think BIG: The large small autoclave with 50 litres and trend-setting product highlights.

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Cliniclave 45

Cliniclave 45

Compact, fast, economical. The large autoclave with 105 liters for reprocessing a sterilization unit in the shortest possible time.

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Cliniclave 45 M

Cliniclave 45 M

The M stands for Magnum: The large 200-liter autoclave sterilizes up to two STE or 70 kg load in record time.

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Expert guidance - just for You.

Get in touch with our international MELAG hygiene experts: We’re here to advise you personally and help you find the best hygiene solution tailored to your requirements.

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What is a large steam sterilizer?

International standards prescribe that large steam sterilizers have a minimum chamber volume of 60 litres or sufficient space for one or more sterilization units. A sterilization unit (STU) is a module with the dimensions 300 x 300 x 600 mm (h x w x d). The high capacity of these steam sterilizers is needed by a central sterile services department (CSSD), also called sterile processing department (SPD) or central supply department (CSD) as an integrated part of hospitals and other larg practices and clinics that performs reprocessing of medical devices, equipment and instruments.

Autoclave Reviews

Enthusiastic customers. For more than 75 years.

More than a seal of quality: Your trust in our autoclaves reflects our commitment to quality, reliability, and service — supporting practices and clinics around the world.

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80 Customer Reviews

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Reviews by Customers

Dentists Hasenhoeheverified

Exclusive advice, convincing quality. Absolutely recommendable!

Wonderful! Received exclusive advice from Mr Trapper today. Tested great Melag appliances....and bought them. Thank you very much! We will recommend you to others.

Dr Gebhardt, Biss45verified

System solution from MELAG

We rely on an autoclave, a sealing device and a thermal disinfector from MELAG for reprocessing. The optimally harmonised system ensures uniform operation and enables new colleagues to be quickly trained. If we have any questions or uncertainties, MELAG support is always on hand to provide reliable assistance.

Tree child fiveverified

Reliable products and outstanding support

Melag is a very nice company. The products seem well thought out and reliable and the service department is also easy to contact and helpful if you have any questions. All in all, a very positive experience.

Dental team in Zehlendorfverified

MELAtherm and Vacuklav - the best combination for us

For us, MELAtherm and Vacuklav simply belong together. The combination gives us a consistently safe feeling in our day-to-day work because our processes are clearly structured and the instruments are reprocessed reliably. With the MELAG system, we know that we can guarantee maximum safety for our patients at all times.

Uwe Johannesverified

Top device with best service

Melag 40 B+ Evolution...best appliance, shortest programme times, best service.

Wendt Dentalverified

Successful switch to the Vacuklav 40B+ Evolution

After 16 years, the old Melag Vacuklav 40B has had its day and has been replaced by its successor, the Melag Vacuklav 40B+ Evolution!

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Cliniclave 45 D

Cliniclave 45 D

Innovative device concept with pass-through: The double-door large autoclave with 110 litres meets the highest demands for infection control.

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Cliniclave 45 MD

Cliniclave 45 MD

Make the impossible possible: The double-door large autoclave with 205 litres guarantees optimal sterilization processes for 2 STE or 70 kg load.

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C45 Accordion Modul Routine-Prüfung
Routine Testing

Trust is good. Control is better.

Based on international standards MELAG recommends the performance of routine checks to ensure the safe operation of a large steam sterilizer.

A Bowie & Dick test serves as proof of the steam penetration of porous materials such as textiles. Simply enter the test package in the large steam sterilizer and start the corresponding Bowie & Dick test program. The Bowie & Dick test provides proof of fast and equal steam penetration into the test package. Please perform the Bowie & Dick test daily and additionally the vacuum test monthly.


An additional batch control can be performed on critical B instruments using a MELAcontrol Helix test body. Our MELAcontrol Helix system enables you to perform safe and reliable checks of the sterilization process even in complex hollow body articles. The colour change of the indicator strips makes for verifiable documentation of the batch approval performed on the XXL colour touch-display, thereby obviating the need for storage of the Helix test body indicator strips in a paper archive.

The supply of the large steam sterilizer with demineralized water can be performed using an external water treatment unit such as the MELAdem 56 reverse osmosis unit from MELAG. Irrespective of your choice of water treatment unit, MELAG Cliniclave 45 series devices are one of the few large steam sterilizers available on the market which comply with the requirements placed on the protection of the drinking water supply by EN1717.

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Accessories

As versatile as you: Find the right accessories for you. And for your MELAG large steam sterilizer.

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Support & Contact

You have questions? We the answers!

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Reprocessing in XXL

Sterilization in large clinics, hospitals and CSSD

Large steam sterilizers are ideal for large practices, outpatient surgery centers, day clinics, medical care centers and smaller hospitals. Whether for 1 StU or 2 StU, as a single-door or double-door unit variant - every Cliniclave 45 is equipped with the same innovative future-oriented technology. This enables safe and efficient sterilization, tailored to the individual needs depending on the number of patients, variety of instruments, spatial situation, regional standards and guidelines.

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Integrated software for documentation and approval

With ProControl, you can provide proof of error-free instrument sterilization in a quick, reliable and paperless way. Because batch approval is performed directly on the display and log storage via CF card or network.

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Record operating times thanks to double jacket technology

Maximum safety in minimum time? That is exactly what the patented double chamber technology ensures. A MELAG patent since 2012. Sterilize partial loads in approx. 20 min. and full loads in approx. 35 min. (excl. drying) with the highest saturated steam quality.

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Optimum drying results with DRYtelligence

No more wet instruments after sterilization? Then benefit from the DRYtelligence algorithm-controlled drying. Intelligent drying ensures optimum drying results and at the same time reduces drying time by up to 80%.

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All-round flexibility with high loading capacities

Made for big tasks: So that every practice or clinic can organize the workflow in the way that suits it best, the Cliniclave 45 Series not only offers outstanding loading capacities of up to 70 kg, but also a wide range of loading options.